Morphologic and Molecular Features of Breast Ductal Carcinoma in Situ
نویسندگان
چکیده
منابع مشابه
breast ductal carcinoma in situ: morphologic and kinetic mri findings
conclusion non-mass-like lesions, lesions with focal or segmental distribution, with a “plateau” enhancement curve type were the most frequent findings of dcis lesions on mri. background adequate diagnosis of ductal carcinoma in situ (dcis) could lead to efficacious treatment. due to the fact that dcis lesions can progress to invasive carcinomas and that the sensitivity of the standard examinat...
متن کاملBreast Ductal Carcinoma in Situ: Morphologic and Kinetic MRI Findings
BACKGROUND Adequate diagnosis of ductal carcinoma in situ (DCIS) could lead to efficacious treatment. Due to the fact that DCIS lesions can progress to invasive carcinomas and that the sensitivity of the standard examination - mammography - is between 70 and 80%, use of a more sensitive diagnostic tool was needed. In detection of DCIS, contrast-enhanced magnetic resonance imaging (CE-MRI) has t...
متن کاملDuctal carcinoma in situ of the breast: morphological and molecular features implicated in progression
The spread of mammographic screening programmes around the world, including in developing countries, has substantially contributed to the diagnosis of small non-palpable lesions, which has increased the detection rate of DCIS (ductal carcinoma in situ). DCIS is heterogeneous in several ways, such as its clinical presentation, morphology and genomic profile. Excellent outcomes have been reported...
متن کاملMolecular markers in ductal carcinoma in situ of the breast.
Gene expression patterns in ductal carcinoma in situ (DCIS), and in invasive, and metastatic breast tumors were determined using serial analysis of gene expression (SAGE). We used mRNA in situ hybridization to examine gene expression at the cellular level and immunohistochemistry on tissue microarrays to determine association between gene expression patterns and histopathologic characteristics ...
متن کاملBreast Ductal Carcinoma In Situ
Ductal carcinoma in situ (DCIS) of the breast is becoming one of the most important diseases diagnosed in preventive medicine screening. The current age-adjusted incidence rate of DCIS is 32.5 per 100,000 women. For women 50–64 years of age, the incidence is approximately 88 per 100,000. Currently, for every 4 diagnoses of invasive breast cancer, there is 1 diagnosis of DCIS. Risk of DCIS is ra...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2019
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2018.07.031